What is already known about this topic?
Data are limited regarding the risks for SARS-CoV-2 infection and hospitalization after COVID-19 vaccination and previous infection.
What is added by this report?
During May–November 2021, case and hospitalization rates were highest among persons who were unvaccinated without a previous diagnosis. Before Delta became the predominant variant in June, case rates were higher among persons who survived a previous infection than persons who were vaccinated alone. By early October, persons who survived a previous infection had lower case rates than persons who were vaccinated alone.
What are the implications for public health practice?
Although the epidemiology of COVID-19 might change as new variants emerge, vaccination remains the safest strategy for averting future SARS-CoV-2 infections, hospitalizations, long-term sequelae, and death. Primary vaccination, additional doses, and booster doses are recommended for all eligible persons. Additional future recommendations for vaccine doses might be warranted as the virus and immunity levels change.
Tuesday, January 25, 2022
Friday, January 21, 2022
Cannabidiol—the non-psychoactive cannabis compound better known as CBD—is a potent blocker of SARS-CoV-2 replication in human cells, new research shows. Not only that, but a survey of real-world patients taking prescribed CBD found a "significant" negative relationship between CBD consumption and COVID-19 infection.
As detailed in a paper published Thursday in the peer-reviewed journal Science Advances by a team of 33 researchers at the University of Chicago and University of Louisville, a survey of 1,212 U.S. patients taking prescribed CBD found that people taking 100 milligrams-per-milliliter oral doses of CBD returned positive COVID-19 tests at much lower rates than control groups with similar medical backgrounds who did not take CBD.
What's interesting to me here is not the actual science. But here's the abstract anyway.
The spread of SARS-CoV-2 and ongoing COVID-19 pandemic underscores the need for new treatments. Here we report that cannabidiol (CBD) inhibits infection of SARS-CoV-2 in cells and mice. CBD and its metabolite 7-OH-CBD, but not THC or other congeneric cannabinoids tested, potently block SARS-CoV-2 replication in lung epithelial cells. CBD acts after viral entry, inhibiting viral gene expression and reversing many effects of SARS-CoV-2 on host gene transcription. CBD inhibits SARS-CoV-2 replication in part by up-regulating the host IRE1 RNase endoplasmic reticulum (ER) stress response and interferon signaling pathways. In matched groups of human patients from the National COVID Cohort Collaborative, CBD (100 mg/ml oral solution per medical records) had a significant negative association with positive SARS-CoV-2 tests. This study highlights CBD as a potential preventative agent for early-stage SARS-CoV-2 infection and merits future clinical trials. We caution against use of non-medical formula-tions including edibles, inhalants or topicals as a preventative or treatment therapy at the present time.
Thursday, January 20, 2022
Oh? Some are better than others? Tell me more, CDC.
Summary of Recent Changes
- Added information to present similar content for masks and respirators
- Clarified that people can choose respirators such as N95s and KN95s, including removing concerns related to supply shortages for N95s
- Clarified that "surgical N95s" are a specific type of respirator that should be reserved for healthcare settings
- Clarified that some types of masks and respirators provide more protection to the wearer than others
- Masking is a critical public health tool for preventing spread of COVID-19, and it is important to remember that any mask is better than no mask.
- To protect yourself and others from COVID-19, CDC continues to recommend that you wear the most protective mask you can that fits well and that you will wear consistently.
- Masks and respirators are effective at reducing transmission of SARS-CoV-2, the virus that causes COVID-19, when worn consistently and correctly.
- Some masks and respirators offer higher levels of protection than others, and some may be harder to tolerate or wear consistently than others. It is most important to wear a well-fitted mask or respirator correctly that is comfortable for you and that provides good protection.
- While all masks and respirators provide some level of protection, properly fitted respirators provide the highest level of protection. Wearing a highly protective mask or respirator may be most important for certain higher risk situations, or by some people at increased risk for severe disease.
- CDC's mask recommendations provide information that people can use to improve how well their masks protect them.
Choosing a Mask or Respirator for Different Situations
Masks and respirators (i.e., specialized filtering masks such as "N95s") can provide different levels of protection depending on the type of mask and how they are used. Loosely woven cloth products provide the least protection, layered finely woven products offer more protection, well-fitting disposable surgical masks and KN95s offer even more protection, and well-fitting NIOSH-approved respirators (including N95s) offer the highest level of protection.
Whatever product you choose, it should provide a good fit (i.e., fitting closely on the face without any gaps along the edges or around the nose) and be comfortable enough when worn properly (covering your nose and mouth) so that you can keep it on when you need to. Learn how to improve how well your mask protects you by visiting CDC's Improve How Your Mask Protects You page.
A respirator has better filtration, and if worn properly the whole time it is in use, can provide a higher level of protection than a cloth or procedural mask. A mask or respirator will be less effective if it fits poorly or if you wear it improperly or take it off frequently. A respirator may be considered in certain situations and by certain people when greater protection is needed or desired.
4. Airborne aerosols and respiratory viruses transmission
Respiratory viruses may be transmitted through indirect contact, direct contact person-to-person, large droplet spray, airborne aerosol, or a combination of all of these. Disease-carrying aerosols contain substances < 5 μm, while infectious disease physicians traditionally consider large droplet sprays to contain substances > 5 μm at close range (6.6 feet or < 2 m). It is generally believed that droplets and aerosols >5 μm settle within 6 feet away from the infected person who produces them, due to gravity (Duguid, 1946; Morawska et al., 2009; Asadi et al., 2019). Nevertheless, the use of 5 μm as a definite for these definitions is not supported by novel aerosol science, and the creation of a false dichotomy between what is considered an aerosol and what has considered a droplet undermines the notion of transmission (Klompas et al., 2020; Prather et al., 2020). The route of virus exposure is crucial to understanding transmission. Aerosols and droplets sprayed on the body and its mucous membranes, a kind of contact transmitter, while aerosols particles are inhaled by the respiratory system (Dhand and Li, 2020). This distinction now follows disease severity, infectious dose, and control strategies. At a close range, both inhalation and contact transmission pathways are possible, but in a longer range, when the droplets have settled rapidly transmission through the inhalation pathway is important. According to aerosol science, the aerosol size is not 5 μm, so an aerosol > 5 μm is inhalable and extends over 6 feet. Also, the aerosols may be formed through the resuspension of static aerosols or settled dust (Duguid, 1946; Prather et al., 2020). The virus is found in saliva or respiratory fluid, which varies in size from aerosols and droplets from 0.2 μm to 100 μm. In general, these aerosols particles and drops are produced through breathing, speaking, and talking with aerosols, coughing, and rapid drops accompanied by coughing (Dhand and Li, 2020; Heyder et al., 1986).
The CDC finally, on January 14th 2022, admitted it.
So, what does this mean? Will the CDC finally back off the mask bullshit and admit it was all theater? Of course not! Don't be silly. No, what they're going to do is double and triple down, and start specifying N-95 respirators for toddlers and everybody else. You can see it in their recommendations sheet.
Lately we've seen the various cabinet ministers and the Prime Minister out there on TV saying that wearing a mask is the wrong idea. The reason they state for this claim is that the mask "gives people a false sense of security."Translated from Official Speak: You people are too stupid to live. This is all far too complicated for your feeble minds to comprehend. Just shut up and do what you're told.
While the federal government is telling us we are a bunch of racists and we shouldn't wear masks to curb the spread of COVID-19, otherwise known as the Kung Flu, the Wuhan Flu, the Chinese Communist BioWeapon Flu, the Bat Flu, and etc... the Premiere of Ontario is saying we need to be making masks right here in Ontario instead of begging China for them.
Welcoming the removal of face coverings in schools, political commentator Sophie Corcoran breaks down as she recalls her experience of wearing a mask in the classroom.
More than 40 physicians are currently being investigated by the College of Physicians and Surgeons of Ontario (CPSO) for promoting unproven treatments for COVID-19 or sharing unverified information about its vaccines, Global News can reveal.
The revelation comes after Ontario Health Minister Christine Elliott publicly urged the CPSO to crack down on a group of doctors accused of spreading unverified medical information about the vaccines, after the situation was brought to light in a Global News investigation.
During a press conference on Wednesday morning to update Ontarians on the province’s fight against the Omicron variant, Elliott labelled the reports “extremely concerning.”
“At a time when it’s never been more important for Ontarians to have confidence in the safety and effectiveness of vaccines, this is unacceptable,” she said.
Sunday, January 16, 2022
Karen attacks nurses:
Three Ontario nurses who have faced discipline for their stances on the pandemic are suing the Canadian Nurses Association (CNA) and a media outlet in British Columbia, with the libel suit seeking $1 million.
Kristen Nagle of London, Kristal Pitter of Tillsonburg and Sara Choujounian of Toronto have been investigated by the College of Nurses of Ontario (CNO) for sharing their controversial views about the pandemic on social media.
Karen attacks doctors: https://www.miamiherald.com/news/coronavirus/article257335847.html
A doctor with decades of experience can't practice medicine after her license was temporarily suspended over complaints that she shared coronavirus misinformation, according to a Maine licensing board. The board has ordered her to undergo a neuropsychological evaluation, it said.
Novak Djokovic left Australia on Sunday evening after losing his final bid to avoid deportation and play in the Australian Open despite being unvaccinated for COVID-19. A court earlier unanimously dismissed the No. 1-ranked tennis player's challenge to cancel his visa.
In a Canadian first, Quebec Premier François Legault announced on Tuesday that a new "health contribution" will have to be paid by residents who haven't received their first dose of a COVID-19 vaccine for non-medical reasons.
Since January 1, the New Cases by Vaccination Status table has shown a significant number of new cases as unvaccinated. This data is not accurate. This table is no longer featured on the dashboard until a review of the information is complete and the data rectified.
Customer in an Etobicoke Costco is arrested and hauled away by cops for not wearing a mask despite having a medical exemption. Allegedly one of the managers of the store is detaining the man alongside police.
Karen is becoming a problem, you ask me.
That's what I'm talking about, right there. Just fucking fire them all. Every single one.
Glenn Youngkin, Virginia's first Republican Governor in more than a decade, wasted no time addressing his campaign pledges, signing nine executive orders and two executive directives. Within hours of being sworn in, Youngkin:
1. Banned the use of CRT and other inherently divisive concepts in schools;
2. Ended school mask mandates;
3. Terminated the entire Parole Board of the Commonwealth of Virginia (all were Democratic appointees);
4. Initiated an investigation into Loudoun County;
5. Established the position of Chief Transformation Officer to review all government agencies, beginning with the Department of Motor Vehicles and the Virginia Employment Commission;
6. Declared Virginia open for business and initiated a review of burdensome Covid regulations;
7. Established a commission prevent human trafficking and provide support to survivors;
8. Established a commission to combat antisemitism;
9. Withdrew from the Regional Greenhouse Gas Initiative (RGGI);
10. Directed all Executive Branch entities to reduce job-killing regulations by at least 25 percent;
11. Rescinded the vaccine mandate for all state employees.
"Meanwhile, new Attorney General Jason Miyares (who was also just sworn in) has terminated the entire Civil Rights Division of the AG's Office (many of them Soros backed lawyers). YOWZA!
That was a MASS firing within a few moments of being sworn in. The MSM are calling it 'insane' and 'mean.'
Friday, January 14, 2022
Yes you read that right. Defense distributed has taken their Ghost Gunner desktop CNC to the next level. They are now offering jigs and code to mill a zero percent receiver (raw billet blank aka brick of aluminum) into a lower receiver. Life finds a way to be ungovernable.
I've talked about this before.There are easier things to make than an AR-15. I'm not going to list them here because Lucy is watching, but a little look at history shows all sorts of things an enterprising lad could make out of aluminum, plastic and steel. If guys can do it by hand in a busted-ass hut in Pakistan, guys can do it in North America with power tools.
As a complement to vaccines, small-molecule therapeutic agents are needed to treat or prevent infections by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants, which cause COVID-19. Affinity selection-mass spectrometry was used for the discovery of botanical ligands to the SARS-CoV-2 spike protein. Cannabinoid acids from hemp (Cannabis sativa) were found to be allosteric as well as orthosteric ligands with micromolar affinity for the spike protein. In follow-up virus neutralization assays, cannabigerolic acid and cannabidiolic acid prevented infection of human epithelial cells by a pseudovirus expressing the SARS-CoV-2 spike protein and prevented entry of live SARS-CoV-2 into cells. Importantly, cannabigerolic acid and cannabidiolic acid were equally effective against the SARS-CoV-2 alpha variant B.1.1.7 and the beta variant B.1.351. Orally bioavailable and with a long history of safe human use, these cannabinoids, isolated or in hemp extracts, have the potential to prevent as well as treat infection by SARS-CoV-2.
Given the juicy nature of this study for juvenile-minded journalists [ha ha, stoners can't catch the 'Rona, ha ha!!!] it will be interesting to see them pass hard on reporting about this result. I prophesy there will be no mention of it anywhere. I found it at Slashdot, not exactly mainstream.
A doctor with decades of experience can’t practice medicine after her license was temporarily suspended over complaints that she shared coronavirus misinformation, according to a Maine licensing board. The board has ordered her to undergo a neuropsychological evaluation, it said. Dr. Meryl J. Nass, who got a license to practice medicine in Maine in 1997, had her license “immediately” suspended for 30 days after a board investigation and review of complaints against her on Jan. 12, according to a suspension order from the Maine Board of Licensure in Medicine.The letter gets very smeary along the way:
“The information received by the Board demonstrates that Dr. Nass is or may be unable to practice medicine with reasonable skill and safety to her patients by reason of mental illness, alcohol intemperance, excessive use of drugs, narcotics, or as a result of a mental or physical condition interfering with the competent practice of medicine,” the evaluation order states. The complaints against Nass include how the board was told she engaged in “public dissemination of ‘misinformation’” about COVID-19 and vaccinations “via a video interview and on her website,” the board said about the October 26, 2021 complaint. It lists several comments Nass made that were subject to the board’s investigation.Sounds like a Karen complained about a social media post, right? Here's the important part:
Other grounds for her suspension include how Nass treated COVID-19 patients with Ivermectin and hydroxychloroquine, according to the board.Now, of note, it does not seem like any of Dr. Nass's actual patients are complaining that the good doctor made them sick with her crazy horse paste witchcraft and fish tank cleaner voodoo. This is activists complaining to the board, and the board coming down on her for making them look bad.
Wednesday, January 05, 2022
The trial is the first of its kind to thoroughly investigate the simultaneous administration of psilocybin. 89 healthy participants with no recent (within 1 year) use of psilocybin were recruited. 60 individuals were randomly picked to receive either a 10mg or 25mg dose of psilocybin in a controlled environment. In addition, all participants were provided with one-to-one support from trained psychotherapists. The remaining 29 participants acted as the control group and received a placebo, also with psychological support. Participants were closely monitored for six to eight hours following administration of psilocybin and then followed up for 12 weeks. During this time, they were assessed for a number of possible changes, including sustained attention, memory, and planning, as well as their ability to process emotions. Throughout the study, there were no instances of anyone withdrawing from the study due to an adverse event, and no consistent trends to suggest that either of the psilocybin doses had any short- or long-term detrimental effects on participants.