Early estimates of case fatality rate (CFR, ratio of deaths divided by documented infections) in the elderly were very high and they played an instrumental role in disseminating both fear and alacrity in dealing with this serious pandemic. Early estimates of CFR from China (48) described CFR of 8% in the age group 70-79 and 14.8% in those ≥80 years. Extremely high CFR estimates were also reported initially from Italy (49) and New York (50). However, the number of infected individuals was much larger than the documented cases (51). Therefore, IFR is much lower than CFR. We are aware of three previous evaluations of age-stratified IFR estimates that combine seroprevalence data with age-specific COVID-19 mortality statistics (4, 5, 52). Levin et al (4) is also the basis for the US CDC pandemic planning scenarios (53). Levin et al report IFR 4.6% at age 75, and 15% at age 85 (4) without separating nursing home deaths.
I use this as an example because it was pointed out at Small Dead Animals that the most an application like that should cost is $250,000 to design, maybe another million to implement at the outside most.
$100,000,000 One hundred million.